Prof. Jörg Vogel
Über
Prof. Jörg Vogel ist seit 2017 Direktor des Helmholtz-Instituts für RNA-basierte Infektionsforschung (HIRI) in Würzburg, wo er schon seit 2009 als Professor und Direktor des Instituts für Molekulare Infektionsbiologie (IMIB) tätig war. Als weltweit anerkannter Wissenschaftler auf dem Gebiet der RNA-Biologie, 2017 mit dem Leibniz-Preis ausgezeichnet, gilt er als Pionier in der Anwendung und Entwicklung von Hochdurchsatz-Sequenziermethoden für die Analyse einzelner infizierter Zellen sowie von Interaktionen zwischen krankheitserregenden Bakterien und ihren Wirten. Er studierte Biochemie an der Humboldt-Universität zu Berlin und am Imperial College, London (GB). 1999 promovierte er an der Humboldt-Universität mit einer Dissertation über
Gruppe II-Intronspleißen . Er forschte 2000/2001 an der Universität Uppsala (Schweden) und 2002/2003 als EMBO-Fellow an der Hebrew University, Jerusalem (Israel), bevor er 2004 eine unabhängige Nachwuchsgruppe am Max-Planck-Institut für Infektionsbiologie in Berlin gründete.
2024
The RNA landscape of the human commensal Segatella copri reveals a small RNA essential for gut colonization
El Mouali Y, Tawk C, Huang KD, Amend L, Lesker TR, Ponath F, Vogel J, Strowig T (2024)
Cell Host & Microbe 32 (11): 1910-1926.e6DOI: 10.1016/j.chom.2024.09.008
Refining the transcriptional landscapes for distinct clades of virulent phages infecting Pseudomonas aeruginosa
Putzeys L, Wicke L, Boon M, van Noort V, Vogel J, Lavigne R (2024)
microLife 5: uqae002DOI: 10.1093/femsml/uqae002
Cooperation of regulatory RNA and the RNA degradosome in transcript surveillance
Bandyra KJ, Fröhlich KS, Vogel J, Rodnina M, Goyal A, Luisi BF (2024)
Nucleic Acids Research 52 (15): 9161-9173DOI: 10.1093/nar/gkae455
Meeting report 'Microbiology 2023: from single cell to microbiome and host', an international interacademy conference in Würzburg
Cossart P, Hacker J, Holden DH, Normark S, Vogel J (2024)
microLife 5: uqae008DOI: 10.1093/femsml/uqae008
Transcriptome fine-mapping in Fusobacterium nucleatum reveals FoxJ, a new σE-dependent small RNA with unusual mRNA activation activity
Ponath F, Zhu Y, Vogel J (2024)
mBio 15 (4): e0353623DOI: 10.1128/mbio.03536-23
Phage proteins target and co-opt host ribosomes immediately upon infection
Gerovac M, Chihara K, Wicke L, Böttcher B, Lavigne R, Vogel J (2024)
Nature Microbiology 9 (3): 787-800DOI: 10.1038/s41564-024-01616-x
Improved RNA stability estimation through Bayesian modeling reveals most Salmonella transcripts have subminute half-lives
Jenniches L, Michaux C, Popella L, Reichardt S, Vogel J, Westermann AJ, Barquist L (2024)
Proceedings of the National Academy of Sciences of the United States of America 121 (14): e2308814121DOI: 10.1073/pnas.2308814121
A comparative analysis of peptide-delivered antisense antibiotics employing diverse nucleotide mimics
Ghosh C, Popella L, Dhamodharan V, Jung J, Dietzsch J, Barquist L, Höbartner C, Vogel J (2024)
RNA 30 (6): 624-643DOI: 10.1261/rna.079969.124
Exploring the transcriptional landscape of phage-host interactions using novel high-throughput approaches
Putzeys L, Wicke L, Brandão A, Boon M, Pires DP, Azeredo J, Vogel J, Lavigne R, Gerovac M (2024)
Current Opinion in Microbiology 77: 102419DOI: 10.1016/j.mib.2023.102419
A global survey of small RNA interactors identifies KhpA and KhpB as major RNA-binding proteins in Fusobacterium nucleatum
Zhu Y, Ponath F, Cosi V, Vogel J (2024)
Nucleic Acids Research 52 (7): 3950-3970DOI: 10.1093/nar/gkae010
Global Hfq-mediated RNA interactome of nitrogen starved Escherichia coli uncovers a conserved post-transcriptional regulatory axis required for optimal growth recovery
McQuail J, Matera G, Gräfenhan T, Bischler T, Haberkant P, Stein F, Vogel J, Wigneshweraraj S (2024)
Nucleic Acids Research 52 (5): 2323-2339DOI: 10.1093/nar/gkad1211
2023
EAM highlights in FEMS 2023: from the Petri dish to planet Earth
Vogel J, de Lorenzo V (2023)
microLife 4: uqad045DOI: 10.1093/femsml/uqad045
Brain-to-gut trafficking of alpha-synuclein by CD11c+ cells in a mouse model of Parkinson's disease
McFleder RL, Makhotkina A, Groh J, Keber U, Imdahl F, Peña Mosca J, Peteranderl A, Wu J, Tabuchi S, Hoffmann J, …, Volkmann J, Ip CW (2023)
Nature Communications 14 (1): 7529DOI: 10.1038/s41467-023-43224-z
A SAM analogue-utilizing ribozyme for site-specific RNA alkylation in living cells
Okuda T, Lenz AK, Seitz F, Vogel J, Höbartner C (2023)
Nature Chemistry 15 (11): 1523-1531DOI: 10.1038/s41557-023-01320-z
RNA-based medicine: from molecular mechanisms to therapy
Sparmann A, Vogel J (2023)
The EMBO Journal 42 (21): e114760DOI: 10.15252/embj.2023114760
Grad-seq analysis of Enterococcus faecalis and Enterococcus faecium provides a global view of RNA and protein complexes in these two opportunistic pathogens
Michaux C, Gerovac M, Hansen EE, Barquist L, Vogel J (2023)
microLife 4: uqac027DOI: 10.1093/femsml/uqac027
Gut Microbiota Contribution to Weight-Independent Glycemic Improvements after Gastric Bypass Surgery
Hankir MK, Kovatcheva-Datchary P, Springer R, Hoffmann A, Vogel J, Seyfried F, Arora T (2023)
Microbiology Spectrum 11 (3): e0510922DOI: 10.1128/spectrum.05109-22
Improved Bacterial Single-Cell RNA-Seq through Automated MATQ-Seq and Cas9-Based Removal of rRNA Reads
Homberger C, Hayward RJ, Barquist L, Vogel J (2023)
mBio 14 (2): e0355722DOI: 10.1128/mbio.03557-22
A primary cell-based in vitro model of the human small intestine reveals host olfactomedin 4 induction in response to Salmonella Typhimurium infection
Däullary T, Imdahl F, Dietrich O, Hepp L, Krammer T, Fey C, Neuhaus W, Metzger M, Vogel J, Westermann AJ, Saliba AE, Zdzieblo D (2023)
Gut Microbes 15 (1): 2186109DOI: 10.1080/19490976.2023.2186109
Design and off-target prediction for antisense oligomers targeting bacterial mRNAs with the MASON webserver
Jung JJ, Popella L, Do PT, Pfau P, Vogel J, Barquist L (2023)
RNA 299 (5): 570-583DOI: 10.1261/rna.079263.122
RNA recording in single bacterial cells using reprogrammed tracrRNAs
Jiao C, Reckstadt C, König F, Homberger C, Yu J, Vogel J, Westermann AJ, Sharma CM, Beisel CL (2023)
Nature Biotechnology 41 (8): 1107-1116DOI: 10.1038/s41587-022-01604-8
A MATQ-seq-Based Protocol for Single-Cell RNA-seq in Bacteria
Homberger C, Saliba AE, Vogel J (2023)
Methods in Molecular Biology 2584: 105-121DOI: 10.1007/978-1-0716-2756-3_4