Prof Alexander Westermann
About
Alexander Westermann studied Molecular Biosciences at the University of Heidelberg (Germany) and worked as a visiting scholar in 2009 at UC Berkeley (California, USA). He obtained his PhD and worked as a Postdoc in the lab of Prof. Jörg Vogel at the Institute of Molecular Infection Biology (IMIB) in Würzburg. In 2017 and 2018, he was a visiting researcher in the labs of Prof. Andreas Bäumler (UC Davis, USA) and Prof. David Holden (Imperial College London, UK). Since March 2018, he has been a Junior Professor at IMIB, and has since led the HOPI group at HIRI. In July 2023, he was appointed to a W2 professorship at the JMU Biocenter.
2024
Global analysis of the RNA-RNA interactome in Acinetobacter baumannii AB5075 uncovers a small regulatory RNA repressing the virulence-related outer membrane protein CarO
Hamrock FJ, Ryan D, Shaibah A, Ershova AS, Mogre A, Sulimani MM, Ben Taarit S, Reichardt S, Hokamp K, Westermann AJ, Kröger C (2024)
Nucleic Acids Research 52 (18): 11283–11300DOI: 10.1093/nar/gkae668
Group B Streptococcus transcriptome when interacting with brain endothelial cells
Vollmuth N, Bridgers BE, Armstrong ML, Wood JF, Gildea AR, Espinal ER, Hooven TA, Barbieri G, Westermann AJ, Sauerwein T, …, Schubert-Unkmeir A, Kim BJ (2024)
Journal of Bacteriology 206 (6): e0008724DOI: 10.1128/jb.00087-24
Improved RNA stability estimation through Bayesian modeling reveals most Salmonella transcripts have subminute half-lives
Jenniches L, Michaux C, Popella L, Reichardt S, Vogel J, Westermann AJ, Barquist L (2024)
Proceedings of the National Academy of Sciences of the United States of America 121 (14): e2308814121DOI: 10.1073/pnas.2308814121
An expanded transcriptome atlas for Bacteroides thetaiotaomicron reveals a small RNA that modulates tetracycline sensitivity
Ryan D, Bornet E, Prezza G, Alampalli SV, Franco de Carvalho T, Felchle H, Ebbecke T, Hayward RJ, Deutschbauer AM, Barquist L, Westermann AJ (2024)
Nature Microbiology 9 (4): 1130-1144DOI: 10.1038/s41564-024-01642-9
CRISPR-based screening of small RNA modulators of bile susceptibility in Bacteroides thetaiotaomicron
Prezza G, Liao C, Reichardt S, Beisel CL, Westermann AJ (2024)
Proceedings of the National Academy of Sciences of the United States of America 121 (6): 1096DOI: 10.1073/pnas.2311323121
Non-professional efferocytosis of Salmonella-infected intestinal epithelial cells in the neonatal host
Zhang K, Repnik U, Diab N, Friske D, Pütz A, Bachmann AZ, Gubbi NMKP, Hensel M, Förstner KU, Westermann AJ, Dupont A, Hornef MW (2024)
The Journal of Experimental Medicine 221 (3)DOI: 10.1084/jem.20231237
CRISPR Interference-Based Functional Small RNA Genomics
Prezza G, Westermann AJ (2024)
Methods in Molecular Biology 2741: 101-116DOI: 10.1007/978-1-0716-3565-0_6
2023
A primary cell-based in vitro model of the human small intestine reveals host olfactomedin 4 induction in response to Salmonella Typhimurium infection
Däullary T, Imdahl F, Dietrich O, Hepp L, Krammer T, Fey C, Neuhaus W, Metzger M, Vogel J, Westermann AJ, Saliba AE, Zdzieblo D (2023)
Gut Microbes 15 (1): 2186109DOI: 10.1080/19490976.2023.2186109
RNA recording in single bacterial cells using reprogrammed tracrRNAs
Jiao C, Reckstadt C, König F, Homberger C, Yu J, Vogel J, Westermann AJ, Sharma CM, Beisel CL (2023)
Nature Biotechnology 41 (8): 1107-1116DOI: 10.1038/s41587-022-01604-8