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Prof Franziska Faber

About

Franziska Faber studied biology at the Martin-Luther University (Halle/Saale, Germany). Her doctoral work at the Robert Koch Institute (Wernigerode, Germany) introduced her to the field of enteric bacterial infections. In 2011, she started her postdoctoral work in the lab of Andreas Bäumler at the University of California (Davis, USA). Here, she studied the mechanisms by which antibiotic treatment lowers “colonization resistance” against the enteric pathogen Salmonella  enterica. More specifically, she explored how inflammation-associated changes in intestinal nutrients contribute to intestinal colonization of S. enterica. In 2018, she joined the Center for Infectious Disease Research (ZINF) in Würzburg as a Young Investigator to study the previously unexplored RNA biology of the intestinal pathogen Clostridioides difficile. Since 2021, she has been a Junior Professor at the Institute of Molecular Infection Biology (IMIB) and has since headed the ROSE group at Julius-Maximilians-Universität (JMU) Würzburg, which is associated with the HIRI. In 2023, she was appointed to a W2 professorship at the Institute for Hygiene and Microbiology at JMU.


2025

The global RNA-binding protein RbpB is a regulator of polysaccharide utilization in Bacteroides thetaiotaomicron

Rüttiger AS, Ryan D, Spiga L, Lamm-Schmidt V, Prezza G, Reichardt S, Langford M, Barquist L, Faber F, Zhu W, Westermann AJ (2025)

Nature Communications 16 (1): 208DOI: 10.1038/s41467-024-55383-8

2024

An sRNA overexpression library reveals AbnZ as a negative regulator of an essential translocation module in Caulobacter crescentus

Velasco-Gomariz M, Sulzer J, Faber F, Fröhlich KS (2024)

Nucleic Acids Research 53 (1): gkae1139DOI: 10.1093/nar/gkae1139

The conserved noncoding RNA ModT coordinates growth and virulence in Clostridioides difficile

Lence T, Sulzer J, Andress K, Gribling-Burrer AS, Lamm-Schmidt V, Barquist L, Smyth RP, Faber F (2024)

PLOS Biology 22 (12): e3002948DOI: 10.1371/journal.pbio.3002948

Formation of the pyruvoyl-dependent proline reductase Prd from Clostridioides difficile requires the maturation enzyme PrdH

Behlendorf C, Diwo M, Neumann-Schaal M, Fuchs M, Körner D, Jänsch L, Faber F, Blankenfeldt W (2024)

PNAS nexus 3 (7): pgae249DOI: 10.1093/pnasnexus/pgae249