Publications of HIRI

2024

The RNA landscape of the human commensal Segatella copri reveals a small RNA essential for gut colonization

El Mouali Y, Tawk C, Huang KD, Amend L, Lesker TR, Ponath F, Vogel J, Strowig T (2024)

Cell Host & Microbe (Online ahead of print)

A resurrected ancestor of Cas12a expands target access and substrate recognition for nucleic acid editing and detection

Jabalera Y, Tascón I, Samperio S, López-Alonso JP, Gonzalez-Lopez M, Aransay AM, Abascal-Palacios G, Beisel CL, Ubarretxena-Belandia I, Perez-Jimenez R (2024)

Nature Biotechnology (Online ahead of print)

Formation of the pyruvoyl-dependent proline reductase Prd from Clostridioides difficile requires the maturation enzyme PrdH

Behlendorf C, Diwo M, Neumann-Schaal M, Fuchs M, Körner D, Jänsch L, Faber F, Blankenfeldt W (2024)

PNAS nexus 3 (7): pgae249

Global analysis of the RNA-RNA interactome in Acinetobacter baumannii AB5075 uncovers a small regulatory RNA repressing the virulence-related outer membrane protein CarO

Hamrock FJ, Ryan D, Shaibah A, Ershova AS, Mogre A, Sulimani MM, Ben Taarit S, Reichardt S, Hokamp K, Westermann AJ, Kröger C (2024)

Nucleic Acids Research 52 (18): 11283–11300

Bacteria conjugate ubiquitin-like proteins to interfere with phage assembly

Hör J, Wolf SG, Sorek R (2024)

Nature 631 (8022): 850-856

The life-saving benefit of dexamethasone in severe COVID-19 is linked to a reversal of monocyte dysregulation

Knoll R, Helbig ET, Dahm K, Bolaji O, Hamm F, Dietrich O, van Uelft M, Müller S, Bonaguro L, Schulte-Schrepping J, …, Aschenbrenner AC, Kurth F (2024)

Cell 187 (16): 4318-4335.e20

Phage anti-CRISPR control by an RNA- and DNA-binding helix-turn-helix protein

Birkholz N, Kamata K, Feussner M, Wilkinson ME, Cuba Samaniego C, Migur A, Kimanius D, Ceelen M, Went SC, Usher B, …, Jackson SA, Fineran PC (2024)

Nature 631 (8021): 670-677

L-Wnk1 Deletion in Smooth Muscle Cells Causes Aortitis and Inflammatory Shift

Quelquejay H, Al-Rifai R, Silvestro M, Vandestienne M, Ferreira I, Mirault T, Henrion D, Zhong X, Santos-Zas I, Goudot G, …, Jeunemaitre X, Ait-Oufella H (2024)

Circulation Research 135 (4): 488-502

TracrRNA reprogramming enables direct PAM-independent detection of RNA with diverse DNA-targeting Cas12 nucleases

Jiao C, Peeck NL, Yu J, Ghaem Maghami M, Kono S, Collias D, Martinez Diaz SL, Larose R, Beisel CL (2024)

Nature Communications 15 (1): 5909

sCIRCLE-An interactive visual exploration tool for single cell RNA-Seq data

Seeger M, Schöls E, Barquist L (2024)

NAR Genomics and Bioinformatics 6 (3): lqae084

Cooperation of regulatory RNA and the RNA degradosome in transcript surveillance

Bandyra KJ, Fröhlich KS, Vogel J, Rodnina M, Goyal A, Luisi BF (2024)

Nucleic Acids Research 52 (15): 9161-9173

A cell-free transcription-translation pipeline for recreating methylation patterns boosts DNA transformation in bacteria

Vento JM, Durmusoglu D, Li T, Patinios C, Sullivan S, Ttofali F, van Schaik J, Yu Y, Wang Y, Barquist L, Crook N, Beisel CL (2024)

Molecular Cell 84 (14): 2785-2796.e4

Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans

Benz F, Camara-Wilpert S, Russel J, Wandera KG, Cepaite R, Ares-Arroyo M, Gomes-Filho JV, Englert F, Kuehn JA, Gloor S, …, Sørensen SJ, Pinilla-Redondo R (2024)

Cell Host & Microbe 32 (6): 875-886.e9

Decoding spatiotemporal transcriptional dynamics and epithelial fibroblast crosstalk during gastroesophageal junction development through single cell analysis

Kumar N, Prakash PG, Wentland C, Kurian SM, Jethva G, Brinkmann V, Mollenkopf HJ, Krammer T, Toussaint C, Saliba AE, …, Gurumurthy RK, Chumduri C (2024)

Nature Communications 15 (1): 3064

Phage proteins target and co-opt host ribosomes immediately upon infection

Gerovac M, Chihara K, Wicke L, Böttcher B, Lavigne R, Vogel J (2024)

Nature Microbiology 9 (3): 787-800

Expanding the flexibility of base editing for high-throughput genetic screens in bacteria

Gawlitt S, Collins SP, Yu Y, Blackman SA, Barquist L, Beisel CL (2024)

Nucleic Acids Research 52 (7): 4079-4097

Improved RNA stability estimation through Bayesian modeling reveals most Salmonella transcripts have subminute half-lives

Jenniches L, Michaux C, Popella L, Reichardt S, Vogel J, Westermann AJ, Barquist L (2024)

Proceedings of the National Academy of Sciences of the United States of America 121 (14): e2308814121

An expanded transcriptome atlas for Bacteroides thetaiotaomicron reveals a small RNA that modulates tetracycline sensitivity

Ryan D, Bornet E, Prezza G, Alampalli SV, Franco de Carvalho T, Felchle H, Ebbecke T, Hayward RJ, Deutschbauer AM, Barquist L, Westermann AJ (2024)

Nature Microbiology 9 (4): 1130-1144

CRISPR-based screening of small RNA modulators of bile susceptibility in Bacteroides thetaiotaomicron

Prezza G, Liao C, Reichardt S, Beisel CL, Westermann AJ (2024)

Proceedings of the National Academy of Sciences of the United States of America 121 (6): 1096

Non-professional efferocytosis of Salmonella-infected intestinal epithelial cells in the neonatal host

Zhang K, Repnik U, Diab N, Friske D, Pütz A, Bachmann AZ, Gubbi NMKP, Hensel M, Förstner KU, Westermann AJ, Dupont A, Hornef MW (2024)

The Journal of Experimental Medicine 221 (3)

Isoform-specific RNA structure determination using Nano-DMS-MaP

Gribling-Burrer AS, Bohn P, Smyth RP (2024)

Nature Protocols 19 (6): 1835-1865

Human cytomegalovirus exploits STING signaling and counteracts IFN/ISG induction to facilitate infection of dendritic cells

Costa B, Becker J, Krammer T, Mulenge F, Durán V, Pavlou A, Gern OL, Chu X, Li Y, Cicin-Šain L, …, Erhard F, Kalinke U (2024)

Nature Communications 15 (1): 1745

Improved prediction of bacterial CRISPRi guide efficiency from depletion screens through mixed-effect machine learning and data integration

Yu Y, Gawlitt S, de Andrade E Sousa LB, Merdivan E, Piraud M, Beisel CL, Barquist L (2024)

Genome Biology 25 (1): 13

Nucleolar detention of NONO shields DNA double-strand breaks from aberrant transcripts

Trifault B, Mamontova V, Cossa G, Ganskih S, Wei Y, Hofstetter J, Bhandare P, Baluapuri A, Nieto B, Solvie D, …, Munschauer M, Burger K (2024)

Nucleic Acids Research 52 (6): 3050-3068

A global survey of small RNA interactors identifies KhpA and KhpB as major RNA-binding proteins in Fusobacterium nucleatum

Zhu Y, Ponath F, Cosi V, Vogel J (2024)

Nucleic Acids Research 52 (7): 3950-3970

SHIFTR enables the unbiased identification of proteins bound to specific RNA regions in live cells

Aydin J, Gabel A, Zielinski S, Ganskih S, Schmidt N, Hartigan CR, Schenone M, Carr SA, Munschauer M (2024)

Nucleic Acids Research 52 (5): e26

Global Hfq-mediated RNA interactome of nitrogen starved Escherichia coli uncovers a conserved post-transcriptional regulatory axis required for optimal growth recovery

McQuail J, Matera G, Gräfenhan T, Bischler T, Haberkant P, Stein F, Vogel J, Wigneshweraraj S (2024)

Nucleic Acids Research 52 (5): 2323-2339

Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection

Torcellan T, Friedrich C, Doucet-Ladevèze R, Ossner T, Solé VV, Riedmann S, Ugur M, Imdahl F, Rosshart SP, Arnold SJ, …, Kastenmüller W, Gasteiger G (2024)

Immunity 57 (1): 124-140.e7

Sequential Antigen-loss and Branching Evolution in Lymphoma after CD19- and CD20-Targeted T-cell Redirecting Therapy

Duell J, Leipold AM, Appenzeller S, Fuhr V, Rauert-Wunderlich H, Da Vià MC, Dietrich O, Toussaint C, Imdahl F, Eisele F, …, Saliba AE, Rasche L (2024)

Blood 143 (8): 685-696

NEAT1 promotes genome stability via m6A methylation-dependent regulation of CHD4

Mamontova V, Trifault B, Gribling-Burrer AS, Bohn P, Boten L, Preckwinkel P, Gallant P, Solvie D, Ade CP, Papadopoulos D, …, Smyth RP, Burger K (2024)

Genes & Development 38 (17-20): 915-930

SARS-CoV-2 antigen rapid detection tests: test performance during the COVID-19 pandemic and the impact of COVID-19 vaccination

Wagenhäuser I, Knies K, Pscheidl T, Eisenmann M, Flemming S, Petri N, McDonogh M, Scherzad A, Zeller D, Gesierich A, …, Gabel A, Krone M (2024)

EBioMedicine (Online ahead of print)

Alternating high-fat diet enhances atherosclerosis by neutrophil reprogramming

Lavillegrand JR, Al-Rifai R, Thietart S, Guyon T, Vandestienne M, Cohen R, Duval V, Zhong X, Yen D, Ozturk M, …, Riksen NP, Ait-Oufella H (2024)

Nature 634 (8033): 447-456

A novel in vitro tubular model to recapitulate features of distal airways: The bronchioid

Maurat E, Raasch K, Leipold AM, Henrot P, Zysman M, Prevel R, Trian T, Krammer T, Bergeron V, Thumerel M, …, Recher G, Dupin I (2024)

The European Respiratory journal 64 (4)

Getting to the root of root-microbe interactions

King WL, Hayward RJ, Goebel M, Fleishman SM, Bauerle TL, Bell TH (2024)

Science Progress 107 (3)

Phages to the rescue: in situ editing of the gut microbiota

Kamm C, Beisel CL (2024)

Trends in Microbiology 32 (10): 934-935

Ten Years of the Synthetic Biology Summer Course at Cold Spring Harbor Laboratory

Haynes KA, Andrews LB, Beisel CL, Chappell J, Cuba Samaniego CE, Dueber JE, Dunlop MJ, Franco E, Lucks JB, Noireaux V, …, Smanski M, Young E (2024)

ACS Synthetic Biology 13 (9): 2635-2642

Neural network-assisted humanisation of COVID-19 hamster transcriptomic data reveals matching severity states in human disease

Friedrich VD, Pennitz P, Wyler E, Adler JM, Postmus D, Müller K, Teixeira Alves LG, Prigann J, Pott F, Vladimirova D, …, Kirsten H, Nouailles G (2024)

EBioMedicine 108: 105312

Transglutaminase-catalyzed covalent

Hamm P, Beckmann D, Worschech R, Braun A, Gutmann M, Korb-Pap A, Lühmann T, Pap T, Meinel L (2024)

European Journal of Pharmaceutics and Biopharmaceutics 203: 114462

Cell-free expression with a quartz crystal microbalance enables rapid, dynamic, and label-free characterization of membrane-interacting proteins

Khakimzhan A, Izri Z, Thompson S, Dmytrenko O, Fischer P, Beisel C, Noireaux V (2024)

Communications Biology 7 (1): 1005

SOX2 interacts with hnRNPK to modulate alternative splicing in mouse embryonic stem cells

Huang Y, Liu Y, Pu M, Zhang Y, Cao Q, Li S, Wei Y, Hou L (2024)

Cell & Bioscience 14 (1): 102

MprF-mediated immune evasion is necessary for Lactiplantibacillus plantarum resilience in the Drosophila gut during inflammation

Arias-Rojas A, Arifah AQ, Angelidou G, Alshaar B, Schombel U, Forest E, Frahm D, Brinkmann V, Paczia N, Beisel CL, Gisch N, Iatsenko I (2024)

PLOS Pathogens 20 (8): e1012462

Characterization and implementation of the MarathonRT template-switching reaction to expand the capabilities of RNA-Seq

Guo LT, Grinko A, Olson S, Leipold A, Graveley B, Saliba AE, Pyle AM (2024)

RNA 30 (11): 1495–1512

Spatial transcriptomics reveals profound subclonal heterogeneity and T-cell dysfunction in extramedullary myeloma

John M, Helal M, Duell J, Mattavelli G, Stanojkovska E, Afrin N, Leipold AM, Steinhardt MJ, Zhou X, Žihala D, …, Riedel A, Rasche L (2024)

Blood (Online ahead of print)

High-throughput transposon mutagenesis in the family Enterobacteriaceae reveals core essential genes and rapid turnover of essentiality

A Ghomi F, Jung JJ, Langridge GC, Cain AK, Boinett CJ, Abd El Ghany M, Pickard DJ, Kingsley RA, Thomson NR, Parkhill J, Gardner PP, Barquist L (2024)

mBio: e0179824

Visually distinguishing between tumor tissue and healthy tissue within ten minutes using proteolytic probes

Reinhardt D, Ter Mors B, Driessen MD, Gutmann M, Faber J, Haug L, Faber AM, Herrmann A, Hamm P, Lühmann T, Linz C, Meinel L (2024)

Sensors & Diagnostics 68 (6): 394

Translation Inhibition Mediated by Interferon-Stimulated Genes during Viral Infections

Smart A, Gilmer O, Caliskan N (2024)

Viruses 16 (7)

Impaired T cells and "memory-like" NK-cell reconstitution is linked to late-onset HCMV reactivation after letermovir cessation

Lauruschkat CD, Muchsin I, Rein AF, Erhard F, Grathwohl D, Dölken L, Köchel C, Nehmer A, Falk CS, Grigoleit GU, …, Wurster S, Kraus S (2024)

Blood advances 8 (11): 2967-2979

Refining the transcriptional landscapes for distinct clades of virulent phages infecting Pseudomonas aeruginosa

Putzeys L, Wicke L, Boon M, van Noort V, Vogel J, Lavigne R (2024)

microLife 5: uqae002

CD8+ T Cells Drive Plaque Smooth Muscle Cell Dedifferentiation in Experimental Atherosclerosis

Schäfer S, Gogiraju R, Rösch M, Kerstan Y, Beck L, Garbisch J, Saliba AE, Gisterå A, Hermanns HM, Boon L, …, Cochain C, Zernecke A (2024)

Arteriosclerosis Thrombosis, and Vascular biology 44 (8): 1852-1872

PEGylated Recombinant Aplysia punctata Ink Toxin Depletes Arginine and Lysine and Inhibits the Growth of Tumor Xenografts

Wolkersdorfer AM, Bergmann B, Adelmann J, Ebbinghaus M, Günther E, Gutmann M, Hahn L, Hurwitz R, Krähmer R, Leenders F, …, Meinel L, Rudel T (2024)

ACS Biomaterials Science & Engineering 10 (6): 3825-3832

An Introductory Guide to Protease Sensitive Linker Design Using Matrix Metalloproteinase 13 as an Example

Hamm P, Meinel L, Driessen MD (2024)

ACS Biomaterials Science & Engineering 10 (6): 3693-3706

Network depth affects inference of gene sets from bacterial transcriptomes using denoising autoencoders

Kion-Crosby W, Barquist L (2024)

Bioinformatics Advances 4 (1): 181

Recruitment of multi-segment genomic RNAs by Bluetongue virus requires a preformed RNA network

Sung PY, Phelan JE, Luo D, Kulasegaran-Shylini R, Bohn P, Smyth RP, Roy P (2024)P., Roy P (2024)

Nucleic Acids Research 52 (14): 8500-8514

Group B Streptococcus transcriptome when interacting with brain endothelial cells

Vollmuth N, Bridgers BE, Armstrong ML, Wood JF, Gildea AR, Espinal ER, Hooven TA, Barbieri G, Westermann AJ, Sauerwein T, …, Schubert-Unkmeir A, Kim BJ (2024)

Journal of Bacteriology 206 (6): e0008724

Characterization of a Human Respiratory Mucosa Model to Study Odorant Metabolism

Mérignac-Lacombe J, Kornbausch N, Sivarajan R, Boichot V, Berg K, Oberwinkler H, Saliba AE, Loos HM, Ehret Kasemo T, Scherzad A, …, Heydel JM, Steinke M (2024)

Journal of Agricultural and Food Chemistry 72 (22): 12696-12706

Sequencing accuracy and systematic errors of nanopore direct RNA sequencing

Liu-Wei W, van der Toorn W, Bohn P, Hölzer M, Smyth RP, von Kleist M (2024)

BMC Genomics 25 (1): 528

TREM2 protects from atherosclerosis by limiting necrotic core formation

Piollet M, Porsch F, Rizzo G, Kapser F, Schulz DJ, Kiss MG, Schlepckow K, Morenas-Rodriguez E, Sen MO, Gropper J, …, Binder CJ, Cochain C (2024)

Nature Cardiovascular Research 3 (3): 269-282

Meeting report 'Microbiology 2023: from single cell to microbiome and host', an international interacademy conference in Würzburg

Cossart P, Hacker J, Holden DH, Normark S, Vogel J (2024)

microLife 5: uqae008

Activated rate-response is associated with increased mortality risk in cardiac device carriers with acute heart failure

Huttelmaier MT, Münsterer S, Morbach C, Sahiti F, Scholz N, Albert J, Gabel A, Angermann C, Ertl G, Frantz S, Störk S, Fischer TH (2024)

PLOS One 19 (4): e0302321

Transcriptome fine-mapping in Fusobacterium nucleatum reveals FoxJ, a new σE-dependent small RNA with unusual mRNA activation activity

Ponath F, Zhu Y, Vogel J (2024)

mBio 15 (4): e0353623

A method to correct for local alterations in DNA copy number that bias functional genomics assays applied to antibiotic-treated bacteria

Sullivan GJ, Barquist L, Cain AK (2024)

mSystems 12: e0066523

RNA helicase IGHMBP2 regulates THO complex to ensure cellular mRNA homeostasis

Prusty AB, Hirmer A, Sierra-Delgado JA, Huber H, Guenther UP, Schlosser A, Dybkov O, Yildirim E, Urlaub H, Meyer KC, …, Erhard F, Fischer U (2024)

Cell Reports 43 (2): 113802

A Hitchhiker's guide to CRISPR editing tools in bacteria : CRISPR can help unlock the bacterial world, but technical and regulatory barriers persist

Krink N, Nikel PI, Beisel CL (2024)

EMBO Reports 25 (4): 1694-1699

An adapted method for Cas9-mediated editing reveals the species-specific role of β-glucoside utilization driving competition between Klebsiella species

Almási ÉdH, Knischewski N, Osbelt L, Muthukumarasamy U, El Mouali Y, Vialetto E, Beisel CL, Strowig T (2024)

Journal of Bacteriology 206 (3): e0031723

A comparative analysis of peptide-delivered antisense antibiotics employing diverse nucleotide mimics

Ghosh C, Popella L, Dhamodharan V, Jung J, Dietzsch J, Barquist L, Höbartner C, Vogel J (2024)

RNA 30 (6): 624-643

CRISPR Interference-Based Functional Small RNA Genomics

Prezza G, Westermann AJ (2024)

Methods in Molecular Biology 2741: 101-116

Exploring the transcriptional landscape of phage-host interactions using novel high-throughput approaches

Putzeys L, Wicke L, Brandão A, Boon M, Pires DP, Azeredo J, Vogel J, Lavigne R, Gerovac M (2024)

Current Opinion in Microbiology 77: 102419

PEGylation of Human Vascular Endothelial Growth Factor

Wolkersdorfer AM, Jugovic I, Scheller L, Gutmann M, Hahn L, Diessner J, Lühmann T, Meinel L (2024)

ACS Biomaterials Science and Engineering 10 (1): 149-155

2023

Brain-to-gut trafficking of alpha-synuclein by CD11c+ cells in a mouse model of Parkinson's disease

McFleder RL, Makhotkina A, Groh J, Keber U, Imdahl F, Peña Mosca J, Peteranderl A, Wu J, Tabuchi S, Hoffmann J, …, Volkmann J, Ip CW (2023)

Nature Communications 14 (1): 7529

Vector-borne Trypanosoma brucei parasites develop in artificial human skin and persist as skin tissue forms

Reuter C, Hauf L, Imdahl F, Sen R, Vafadarnejad E, Fey P, Finger T, Jones NG, Walles H, Barquist L, …, Groeber-Becker F, Engstler M (2023)

Nature Communications 14 (1): 7660

Interrogating two extensively self-targeting Type I CRISPR-Cas systems in Xanthomonas albilineans reveals distinct anti-CRISPR proteins that block DNA degradation

Wimmer F, Englert F, Wandera KG, Alkhnbashi OS, Collins SP, Backofen R, Beisel CL (2023)

Nucleic Acids Research 52 (2): 769-783

Microglia-mediated demyelination protects against CD8+ T cell-driven axon degeneration in mice carrying PLP defects

Groh J, Abdelwahab T, Kattimani Y, Hörner M, Loserth S, Gudi V, Adalbert R, Imdahl F, Saliba AE, Coleman M, …, Simons M, Martini R (2023)

Nature Communications 14 (1): 6911

A SAM analogue-utilizing ribozyme for site-specific RNA alkylation in living cells

Okuda T, Lenz AK, Seitz F, Vogel J, Höbartner C (2023)

Nature Chemistry 15 (11): 1523-1531

RNA-based medicine: from molecular mechanisms to therapy

Sparmann A, Vogel J (2023)

The EMBO Journal 42 (21): e114760

Cytosolic Ptbp2 modulates axon growth in motoneurons through axonal localization and translation of Hnrnpr

Salehi S, Zare A, Prezza G, Bader J, Schneider C, Fischer U, Meissner F, Mann M, Briese M, Sendtner M (2023)

Nature Communications 14 (1): 4158

A predicted CRISPR-mediated symbiosis between uncultivated archaea

Esser SP, Rahlff J, Zhao W, Predl M, Plewka J, Sures K, Wimmer F, Lee J, Adam PS, McGonigle J, …, Zhang Y, Probst AJ (2023)

Nature Microbiology 8 (9): 1619-1633

Th17.1 cell driven sarcoidosis-like inflammation after anti-BCMA CAR T cells in multiple myeloma

Leipold AM, Werner RA, Düll J, Jung P, John M, Stanojkovska E, Zhou X, Hornburger H, Ruckdeschel A, Dietrich O, …, Saliba AE, Rasche L (2023)

Leukemia 37 (3): 650-658

Myocardial Milieu Favors Local Differentiation of Regulatory T Cells

Delgobo M, Weiß E, ElDin Ashour D, Richter L, Popiolkowski L, Arampatzi P, Stangl V, Arias-Loza P, Mariotti-Ferrandiz E, Rainer PP, …, Frantz S, Campos Ramos G (2023)

Circulation Research 132 (5): 565-582

Systematically attenuating DNA targeting enables CRISPR-driven editing in bacteria

Collias D, Vialetto E, Yu J, Co K, Almási ÉDH, Rüttiger AS, Achmedov T, Strowig T, Beisel CL (2023)

Nature Communications 14 (1): 680

RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2

Bravo JPK, Hallmark T, Naegle B, Beisel CL, Jackson RN, Taylor DW (2023)

Nature 613 (7944): 582-587

Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA

Dmytrenko O, Neumann GC, Hallmark T, Keiser DJ, Crowley VM, Vialetto E, Mougiakos I, Wandera KG, Domgaard H, Weber J, …, Jackson RN, Beisel CL (2023)

Nature 613 (7944): 588-594

RNA recording in single bacterial cells using reprogrammed tracrRNAs

Jiao C, Reckstadt C, König F, Homberger C, Yu J, Vogel J, Westermann AJ, Sharma CM, Beisel CL (2023)

Nature Biotechnology 41 (8): 1107-1116

Cis-mediated interactions of the SARS-CoV-2 frameshift RNA alter its conformations and affect function

Pekarek L, Zimmer MM, Gribling-Burrer AS, Buck S, Smyth RP, Caliskan N (2023)

Nucleic Acids Research 51 (2): 728–743

Integrated single-cell analysis based classification of vascular mononuclear phagocytes in mouse and human atherosclerosis

Zernecke A, Erhard F, Weinberger T, Schulz C, Ley K, Saliba AE, Cochain C (2023)

Cardiovascular Research 119 (8): 1676-1689

Dynamics of monocyte-derived macrophage diversity in experimental myocardial infarction

Rizzo G, Gropper J, Piollet M, Vafadarnejad E, Rizakou A, Bandi SR, Arampatzi P, Krammer T, DiFabion N, Dietrich O, …, Saliba AE, Cochain C (2023)

Cardiovascular Research 119 (3): 772-785

Rapid neutrophil mobilisation by VCAM-1+ endothelial extracellular vesicles

Akbar N, Braithwaite AT, Corr EM, Koelwyn GJ, van Solingen C, Cochain C, Saliba AE, Corbin A, Pezzolla D, Møller Jørgensen M, …, Melling GE, Shanmuganathan M (2023)

Cardiovascular Research 119 (1): 236-251

EAM highlights in FEMS 2023: from the Petri dish to planet Earth

Vogel J, de Lorenzo V (2023)

microLife 4: uqad045

Discovery of phage determinants that confer sensitivity to bacterial immune systems

Stokar-Avihail A, Fedorenko T, Hör J, Garb J, Leavitt A, Millman A, Shulman G, Wojtania N, Melamed S, Amitai G, Sorek R (2023)

Cell 186 (9): 1863-1876.e16

Bile Is a Selective Elevator for Mucosal Mechanics and Transport

Hanio S, Möllmert S, Möckel C, Choudhury S, Höpfel AI, Zorn T, Endres S, Schlauersbach J, Scheller L, Keßler C, …, Guck J, Meinel L (2023)

Molecular Pharmaceutics 20 (12): 6151-6161

Matrix Metalloproteinase-Responsive Delivery of PEGylated Fibroblast Growth Factor 2

Gutmann M, Reinhardt D, Seidensticker C, Raschig M, Hahn L, Moscaroli A, Behe M, Meinel L, Lühmann T (2023)

ACS Biomaterials Science & Engineering 10 (1): 156-165

Ribosome profiling reveals the fine-tuned response of Escherichia coli to mild and severe acid stress

Schumacher K, Gelhausen R, Kion-Crosby W, Barquist L, Backofen R, Jung K (2023)

mSystems 8 (6): e0103723

Seropositivity of Borrelia burgdorferi s.l. in Germany-an analysis across four German National Cohort (NAKO) study sites

Hassenstein MJ, Pischon T, Karch A, Peters A, Kerrinnes T, Teismann H, Schneider A, Thierry S, Moreno Velásquez I, Janke J, Kemmling Y, Castell S (2023)

Scientific Reports 13 (1): 21087

SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9

Schmidt N, Ganskih S, Wei Y, Gabel A, Zielinski S, Keshishian H, Lareau CA, Zimmermann L, Makroczyova J, Pearce C, …, Erhard F, Munschauer M (2023)

Cell 186 (22): 4834-4850.e23

The development of matrix-metalloproteinase responsive sensors for the machine-independent detection of oral inflammation

Ter Mors B, Driessen M. D., Seher A, Haubitz I. R., Raschig M, Nowak M, Jockel-Schneider Y, Linz C, Meinel L (2023)

Sensors & Diagnostics 2 (4): 867-877

Shortened CRISPR-Cas9 arrays enable multiplexed gene targeting in bacteria from a smaller DNA footprint

Gawlitt S, Liao C, Achmedov T, Beisel CL (2023)

RNA Biology 20 (1): 666-680

For the CRISPR Fan(zor)atics: RNA-guided DNA endonucleases discovered in eukaryotes

Patinios C, Beisel CL (2023)

Molecular Cell 83 (17): 3046-3048

Bioconjugation of a Fibroblast Activation Protein Targeted Interleukin-4

Ruopp M, Zhu S, Worschech R, Haas D, Maschauer S, Prante O, Meinel L, Lühmann T (2023)

ACS Biomaterials Science & Engineering 9 (10): 5580-5588

The HSV-1 ICP22 protein selectively impairs histone repositioning upon Pol II transcription downstream of genes

Djakovic L, Hennig T, Reinisch K, Milic A, Whisnant AW, Wolf K, Weiß E, Haas T, Grothey A, Jürges CS, …, Friedel CC, Dölken L (2023)

Nature Communications 14 (1): 4591

Advanced fluorescence microscopy in respiratory virus cell biology

Xie E, Ahmad S, Smyth RP, Sieben C (2023)

Advances in Virus Research 116: 123-172

Genetic inhibition of CARD9 accelerates the development of atherosclerosis in mice through CD36 dependent-defective autophagy

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International Journal of Molecular Sciences 22 (5): 2276

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Nature Microbiology 6 (4): 533

A Code of Ethics for Gene Drive Research

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Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19

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The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer

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Dynamics of Cardiac Neutrophil Diversity in Murine Myocardial Infarction

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Single-cell RNA-sequencing reports growth-condition-specific global transcriptomes of individual bacteria

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Nature Microbiology 5 (10): 1202–1206

A high-resolution transcriptome map identifies small RNA regulation of metabolism in the gut microbe Bacteroides thetaiotaomicron

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Nature Communications 11 (1): 3557

Severe COVID-19 is marked by a dysregulated myeloid cell compartment

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Dual RNA-seq of Orientia tsutsugamushi informs on host-pathogen interactions for this neglected intracellular human pathogen

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An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria

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The minimal meningococcal ProQ protein has an intrinsic capacity for structure-based global RNA recognition

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Nucleic Acids Research 44 (15): 7385-94

The target spectrum of SdsR small RNA in Salmonella

Fröhlich KS, Haneke K, Papenfort K, Vogel J (2016)

Nucleic Acids Research 44 (21): 10406-22

A 3' UTR-Derived Small RNA Provides the Regulatory Noncoding Arm of the Inner Membrane Stress Response

Chao Y, Vogel J (2016)

Molecular Cell 61 (3): 352-363

Choreography of molecular movements during ribosome progression along mRNA

Belardinelli R, Sharma H, Caliskan N, Cunha CE, Peske F, Wintermeyer W, Rodnina MV (2016)

Nature Structural & Molecular Biology 23 (4): 342-8

Single-cell RNA-seq ties macrophage polarization to growth rate of intracellular Salmonella

Saliba AE, Li L, Westermann AJ, Appenzeller S, Stapels DA, Schulte LN, Helaine S, Vogel J (2016)

Nature Microbiology 2: 16206

Identifying and Visualizing Functional PAM Diversity across CRISPR-Cas Systems

Leenay RT, Maksimchuk KR, Slotkowski RA, Agrawal RN, Gomaa AA, Briner AE, Barrangou R, Beisel CL (2016)

Molecular Cell 62 (1): 137-47

Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings

Feasey NA, Hadfield J, Keddy KH, Dallman TJ, Jacobs J, Deng X, Wigley P, Barquist L, Langridge GC, Feltwell T, …, Gordon MA, Thomson NR (2016)

Nature Genetics 48 (10): 1211-1217

Dual RNA-seq unveils noncoding RNA functions in host-pathogen interactions

Westermann AJ, Forstner KU, Amman F, Barquist L, Chao Y, Schulte LN, Muller L, Reinhardt R, Stadler PF, Vogel J (2016)

Nature 529 (7587): 496-501

SBE Supplement: Synthetic Biology – Engineering Genes with CRISPR-Cas9

Luo ML, Beisel CL (2016)

American Institute of Chemical Engineers

cis-Encoded Small RNAs, a Conserved Mechanism for Repression of Polysaccharide Utilization in Bacteroides

Cao Y, Förstner KU, Vogel J, Smith CJ (2016)

Journal of Bacteriology 198 (18): 2410-8

The primary transcriptome of the Escherichia coli O104:H4 pAA plasmid and novel insights into its virulence gene expression and regulation

Berger P, Knödler M, Förstner KU, Berger M, Bertling C, Sharma CM, Vogel J, Karch H, Dobrindt U, Mellmann A (2016)

Scientific Reports 6: 35307

Synthetic Biology - Engineering Genes with CRISPR-Cas9

Luo ML, Beisel CL (2016)

CEP Magazine September

Rethinking the Hierarchy of Sugar Utilization in Bacteria

Beisel CL, Afroz T (2016)

Journal of Bacteriology 198 (3): 374-376

Current and future prospects for CRISPR-based tools in bacteria

Luo ML, Leenay RT, Beisel CL (2016)

Biotechnology and Bioengineering 113 (5): 930-43

Natural mutations in a Staphylococcus aureus virulence regulator attenuate cytotoxicity but permit bacteremia and abscess formation

Das S, Lindemann C, Young BC, Muller J, Österreich B, Ternette N, Winkler A, Paprotka K, Reinhardt R, Förstner KU, …, Wyllie DH, Fraunholz MJ (2016)

PNAS 113 (22): E3101-10

An NK Cell Perforin Response Elicited via IL-18 Controls Mucosal Inflammation Kinetics during Salmonella Gut Infection

Müller AA, Dolowschiak T, Sellin ME, Felmy B, Verbree C, Gadient S, Westermann AJ, Vogel J, LeibundGut-Landmann S, Hardt W (2016)

PLOS Pathogens 12 (6): e1005723

Gifsy-1 Prophage IsrK with Dual Function as Small and Messenger RNA Modulates Vital Bacterial Machineries

Hershko-Shalev T, Odenheimer-Bergman A, Elgrably-Weiss M, Ben-Zvi T, Govindarajan S, Seri H, Papenfort K, Vogel J, Altuvia S (2016)

PLOS Genetics 12 (4): e1005975

Emerging roles of RNA modifications in bacteria

Marbaniang CN, Vogel J (2016)

Current Opinion in Microbiology 30: 50-57

HIV-1 Mutation and Recombination Rates Are Different in Macrophages and T-cells

Cromer D, Schlub TE, Smyth RP, Grimm AJ, Chopra A, Mallal S, Davenport MP, Mak J (2016)

Viruses 8 (4): 118

A step forward understanding HIV-1 diversity

Smyth RP, Negroni M (2016)

Retrovirology 13: 27

The Life-Cycle of the HIV-1 Gag-RNA Complex

Mailler E, Bernacchi S, Marquet R, Paillart J, Vivet-Boudou V, Smyth RP (2016)

Viruses 8 (9): E248

MIMEAnTo: profiling functional RNA in mutational interference mapping experiments

Smith MR, Smyth RP, Marquet R, Kleist M (2016)

Bioinformatics 32 (21): 3369-3370

Grad-seq guides the discovery of ProQ as a major small RNA-binding protein

Smirnov A, Förstner KU, Holmqvist E, Otto A, Günster R, Becher D, Reinhardt R, Vogel J (2016)

PNAS 113 (41): 11591-11596

Global RNA recognition patterns of post-transcriptional regulators Hfq and CsrA revealed by UV crosslinking in vivo

Holmqvist E, Wright PR, Li L, Bischler T, Barquist L, Reinhardt R, Backofen R, Vogel J (2016)

The EMBO Journal 35 (9): 991-1011

The TraDIS toolkit: sequencing and analysis for dense transposon mutant libraries

Barquist L, Mayho M, Cummins C, Cain AK, Boinett CJ, Page AJ, Langridge GC, Quail MA, Keane JA, Parkhill J (2016)

Bioinformatics 32 (7): 1109-11

Studying RNA Homology and Conservation with Infernal: From Single Sequences to RNA Families

Barquist L, Burge SW, Gardner PP (2016)

Current Protocols in Bioinformatics 54: 12.13.1-12.13.25

Molecular phenotyping of infection-associated small non-coding RNAs

Barquist L, Westermann AJ, Vogel J (2016)

Philosophical Transactions of the Royal Society of London B: Biological Sciences 371 (1707): 20160081

The in vitro and in vivo effects of constitutive light expression on a bioluminescent strain of the mouse enteropathogen Citrobacter rodentium

Read HM, Mills G, Johnson S, Tsai P, Dalton J, Barquist L, Print CG, Patrick WM, Wiles S (2016)

PeerJ 4: e2130

A profile-based method for identifying functional divergence of orthologous genes in bacterial genomes

Wheeler NE, Barquist L, Kingsley RA, Gardner PP (2016)

Bioinformatics 32 (23): 3566-3574

2015

Changed in translation: mRNA recoding by -1 programmed ribosomal frameshifting

Caliskan N, Peske F, Rodnina MV (2015)

Trends in Biochemical Sciences 40 (5): 265-74

Self‐Assembled DNA Nanoclews for the Efficient Delivery of CRISPR–Cas9 for Genome Editing

Sun W, Ji W, Hall JM, Hu Q, Wang C, Beisel CL, Gu Z (2015)

Angewandte Chemie International Edition 54 (41): 12029-33

The end is not the end: remnants of tRNA precursors live on to sponge up small regulatory RNAs

Ziebuhr W, Vogel J (2015)

Molecular Cell 58 (3): 389-90

Mutational interference mapping experiment (MIME) for studying RNA structure and function

Smyth RP, Despons L, Huili G, Bernacchi S, Hijnen M, Mak J, Jossinet F, Weixi L, Paillart J, Kleist M, Marquet R (2015)

Nature Methods 12 (9): 866-72

The systematic analysis of protein-lipid interactions comes of age

Saliba AE, Vonkova I, Gavin A (2015)

Nature Reviews Molecular Cell Biology 16 (12): 753-61

Accelerating Discovery and Functional Analysis of Small RNAs with New Technologies

Barquist L, Vogel J (2015)

Annual Review of Genetics 49: 367-94

Inflammation-associated alterations to the intestinal microbiota reduce colonization resistance against non-typhoidal Salmonella during concurrent malaria parasite infection

Mooney JP, Lokken KL, Byndloss MX, George MD, Velazquez EM, Faber F, Butler BP, Walker GT, Ali MM, Potts R, …, Luckhart S, Tsolis RM (2015)

Scientific Reports 5: 14603

Integrative, ligand-responsive microRNAs

Smolke CD, Beisel CL (2015)

Patent (US9145555B2)

Lipid Cooperativity as a General Membrane-Recruitment Principle for PH Domains

Vonkova I, Saliba AE, Deghou S, Anand K, Ceschia S, Doerks T, Galih A, Kugler KG, Maeda K, Rybin V, …, Bork P, Gavin A (2015)

Cell Reports 12 (9): 1519-30

Comprehensive Protein Interactome Analysis of a Key RNA Helicase: Detection of Novel Stress Granule Proteins

Bish R, Cuevas-Polo N, Cheng Z, Hambardzumyan D, Munschauer M, Landthaler M, Vogel C (2015)

Biomolecules 5 (3): 1441-66

Trade-offs in engineering sugar utilization pathways for titratable control

Afroz T, Biliouris K, Boykin KE, Kaznessis Y, Beisel CL (2015)

ACS Synthetic Biology 4 (2): 141-9

Impact of Residual Inducer on Titratable Expression Systems

Afroz T, Luo ML, Beisel CL (2015)

PLOS One 10 (9): e0137421

High-throughput analysis of gene essentiality and sporulation in Clostridium difficile

Dembek M, Barquist L, Boinett CJ, Cain AK, Mayho M, Lawley TD, Fairweather NF, Fagan RP (2015)

mBio 6 (2): e02383

Small RNA-based feedforward loop with AND-gate logic regulates extrachromosomal DNA transfer in Salmonella

Papenfort K, Espinosa E, Casadesús J, Vogel J (2015)

PNAS 112 (34): E4772-81

dRNA-Seq Reveals Genomewide TSSs and Noncoding RNAs of Plant Beneficial Rhizobacterium Bacillus amyloliquefaciens FZB42

Fan B, Li L, Chao Y, Förstner K, Vogel J, Borriss R, Wu X (2015)

PLOS One 10 (11): e0142002

Cross talk between ABC transporter mRNAs via a target mRNA-derived sponge of the GcvB small RNA

Miyakoshi M, Chao Y, Vogel J (2015)

The EMBO Journal 34 (11): 1478-92

Investigating CRISPR RNA Biogenesis and Function Using RNA-seq

Heidrich N, Dugar G, Vogel J, Sharma CM (2015)

In: CRISPR: Methods and protocols (eds Lundgren M, Charpentier E, Fineran PC), Methods Mol Biol (Methods in Molecular Biology) 1311: 1-21

Regulatory small RNAs from the 3' regions of bacterial mRNAs

Miyakoshi M, Chao Y, Vogel J (2015)

Current Opinion in Microbiology 24: 132-9

Genome-wide transcription start site profiling in biofilm-grown Burkholderia cenocepacia J2315

Sass AM, van Acker H, Förstner KU, van Nieuwerburgh F, Deforce D, Vogel J, Coenye T (2015)

BMC Genomics 16: 775

Dual 3'Seq using deepSuperSAGE uncovers transcriptomes of interacting Salmonella enterica Typhimurium and human host cells

Afonso-Grunz F, Hoffmeier K, Müller S, Westermann AJ, Rotter B, Vogel J, Winter P, Kahl G (2015)

BMC Genomics 16: 323

Evaluation of anti-HIV-1 mutagenic nucleoside analogues

Vivet-Boudou V, Isel C, El Safadi Y, Smyth RP, Laumond G, Moog C, Paillart J, Marquet R (2015)

The Journal of Biological Chemistry 290 (1): 371-83

Properties of HIV-1 associated cholesterol in addition to raft formation are important for virus infection

Hawkes D, Jones KL, Smyth RP, Pereira CF, Bittman R, Jaworowski A, Mak J (2015)

Virus Research 210: 18-21

Repurposing endogenous type I CRISPR-Cas systems for programmable gene repression

Luo ML, Mullis AS, Leenay RT, Beisel CL (2015)

Nucleic Acids Research 43 (1): 674-81

Patterns of genome evolution that have accompanied host adaptation in Salmonella

Langridge GC, Fookes M, Connor TR, Feltwell T, Feasey N, Parsons BN, Seth-Smith HM, Barquist L, Stedman A, Humphrey T, …, Dougan G, Thomson NR (2015)

PNAS 112 (3): 863-8

Signatures of adaptation in human invasive Salmonella Typhimurium ST313 populations from sub-Saharan Africa

Okoro CK, Barquist L, Connor TR, Harris SR, Clare S, Stevens MP, Arends MJ, Hale C, Kane L, Pickard DJ, …, Dougan G, Kingsley RA (2015)

PLOS Neglected Tropical Diseases 9 (3): e0003611

2014

MOV10 Is a 5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs

Gregersen LH, Schueler M, Munschauer M, Mastrobuoni G, Chen W, Kempa S, Dieterich C, Landthaler M (2014)

Molecular Cell 54 (4): 573-85

Differential protein occupancy profiling of the mRNA transcriptome

Schueler M, Munschauer M, Gregersen LH, Finzel A, Loewer A, Chen W, Landthaler M, Dieterich C (2014)

Genome Biology 15 (1): R15

A CRISPR design for next-generation antimicrobials

Beisel CL, Gomaa AA, Barrangou R (2014)

Genome Biology 15 (11): 516

Guide RNA functional modules direct Cas9 activity and orthogonality

Briner AE, Donohoue PD, Gomaa AA, Selle K, Slorach EM, Nye CH, Haurwitz RE, Beisel CL, May AP, Barrangou R (2014)

Molecular Cell 56 (2): 333-339

A bacterial seek-and-destroy system for foreign DNA

Vogel J (2014)

Science 344 (6187): 972-3

Programmed -1 frameshifting by kinetic partitioning during impeded translocation

Caliskan N, Katunin VI, Belardinelli R, Peske F, Rodnina MV (2014)

Cell 157 (7): 1619-31

Specific recognition of the HIV-1 genomic RNA by the Gag precursor

Abd El-Wahab EW, Smyth RP, Mailler E, Bernacchi S, Vivet-Boudou V, Hijnen M, Jossinet F, Mak J, Paillart J, Marquet R (2014)

Nature Communications 5: 4304

A quantitative liposome microarray to systematically characterize protein-lipid interactions

Saliba AE, Vonkova I, Ceschia S, Findlay GM, Maeda K, Tischer C, Deghou S, van Noort V, Bork P, Pawson T, Ellenberg J, Gavin A (2014)

Nature Methods 11 (1): 47-50

The impact of intestinal inflammation on the nutritional environment of the gut microbiota

Faber F, Bäumler AJ (2014)

Immunology Letters 162 (2 Pt A): 48-53

Salmonella enterica Serovar Typhi conceals the invasion-associated type three secretion system from the innate immune system by gene regulation

Winter SE, Winter MG, Poon V, Keestra AM, Sterzenbach T, Faber F, Costa LF, Cassou F, Costa EA, Alves GE, …, Santos RL, Bäumler AJ (2014)

PLOS Pathogens 10 (7): e1004207

Construction of ligand-responsive microRNAs that operate through inhibition of Drosha processing

Beisel CL, Bloom RJ, Smolke CD (2014)

In: Artificial Riboswitches (ed Ogawa A), Methods Mol Biol 1111: 259-67

Identification and Characterization of Small Non-coding RNAs in Bacteria

Podkaminski D, Bouvier M, Vogel J (2014)

136: 719-786

READemption-a tool for the computational analysis of deep-sequencing-based transcriptome data

Förstner KU, Vogel J, Sharma CM (2014)

Bioinformatics 30 (23): 3421-3

High-resolution profiling of protein occupancy on polyadenylated RNA transcripts

Munschauer M, Schueler M, Dieterich C, Landthaler M (2014)

Methods 65 (3): 302-9

Bacterial sugar utilization gives rise to distinct single-cell behaviours

Afroz T, Biliouris K, Kaznessis Y, Beisel CL (2014)

Molecular Microbiology 93 (6): 1093-1103

Meeting report: Regulating with RNA in Bacteria 2013

Vogel J, Gottesman S, Belasco J, Narberhaus F (2014)

RNA Biology 11 (5): 403-12

Small RNA functions in carbon metabolism and virulence of enteric pathogens

Papenfort K, Vogel J (2014)

Frontiers in Cellular and Infection Microbiology 4: 91

Recognition of the small regulatory RNA RydC by the bacterial Hfq protein

Dimastrogiovanni D, Fröhlich KS, Bandyra KJ, Bruce HA, Hohensee S, Vogel J, Luisi BF (2014)

eLife 3: e05375

Differential RNA-seq: the approach behind and the biological insight gained

Sharma CM, Vogel J (2014)

Current Opinion in Microbiology 19: 97-105

Identifying recombination hot spots in the HIV-1 genome

Smyth RP, Schlub TE, Grimm AJ, Waugh C, Ellenberg P, Chopra A, Mallal S, Cromer D, Mak J, Davenport MP (2014)

Journal of Virology 88 (5): 2891-902

Fifteen to twenty percent of HIV substitution mutations are associated with recombination

Schlub TE, Grimm AJ, Smyth RP, Cromer D, Chopra A, Mallal S, Venturi V, Waugh C, Mak J, Davenport MP (2014)

Journal of Virology 88 (7): 3837-49

Single-cell RNA-seq: advances and future challenges

Saliba AE, Westermann AJ, Gorski SA, Vogel J (2014)

Nucleic Acids Research 42 (14): 8845-60

Programmable removal of bacterial strains by use of genome-targeting CRISPR-Cas systems

Gomaa AA, Klumpe HE, Luo ML, Selle K, Barrangou R, Beisel CL (2014)

mBio 5 (1): e00928-13

Functional genomics reveals that Clostridium difficile Spo0A coordinates sporulation, virulence and metabolism

Pettit LJ, Browne HP, Yu L, Smits WK, Fagan RP, Barquist L, Martin MJ, Goulding D, Duncan SH, Flint HJ, …, Choudhary JS, Lawley TD (2014)

BMC Genomics 15: 160

Robust identification of noncoding RNA from transcriptomes requires phylogenetically-informed sampling

Lindgreen S, Umu SU, Lai AS, Eldai H, Liu W, McGimpsey S, Wheeler NE, Biggs PJ, Thomson NR, Barquist L, Poole AM, Gardner PP (2014)

PLOS Computational Biology 10 (10): e1003907

Parallel independent evolution of pathogenicity within the genus Yersinia

Reuter S, Connor TR, Barquist L, Walker D, Feltwell T, Harris SR, Fookes M, Hall ME, Petty NK, Fuchs TM, …, McNally A, Thomson NR (2014)

PNAS 111 (18): 6768-73

An introduction to RNA databases

Hoeppner MP, Barquist L, Gardner PP (2014)

In: RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods (eds Gorodkin J, Ruzzo W), Methods Mol Biol 1097: 107-23

2013

Same same but different: new structural insight into CRISPR-Cas complexes

Heidrich N, Vogel J (2013)

Molecular Cell 52 (1): 4-7

Circular RNAs are a large class of animal RNAs with regulatory potency

Memczak S, Jens M, Elefsinioti A, Torti F, Krueger J, Rybak A, Maier L, Mackowiak SD, Gregersen LH, Munschauer M, …, Le Noble F, Rajewsky N (2013)

Nature 495 (7441): 333-8

β-Lactam antibiotics promote bacterial mutagenesis via an RpoS-mediated reduction in replication fidelity

Gutierrez A, Laureti L, Crussard S, Abida H, Rodríguez-Rojas A, Blázquez J, Baharoglu Z, Mazel D, Darfeuille F, Vogel J, Matic I (2013)

Nature Communications 4: 1610

Processing-Independent CRISPR RNAs Limit Natural Transformation in Neisseria meningitidis

Zhang Y, Heidrich N, Ampattu BJ, Gunderson CW, Seifert HS, Schoen C, Vogel J, Sontheimer EJ (2013)

Molecular Cell 50 (4): 488-503

Targeted decay of a regulatory small RNA by an adaptor protein for RNase E and counteraction by an anti-adaptor RNA

Göpel Y, Papenfort K, Reichenbach B, Vogel J, Görke B (2013)

Genes & Development 27 (5): 552-64

A small RNA activates CFA synthase by isoform-specific mRNA stabilization

Fröhlich KS, Papenfort K, Fekete A, Vogel J (2013)

The EMBO Journal 32 (22): 2963-79

CRISPRs extending their reach: prokaryotic RNAi protein Cas9 recruited for gene regulation

Heidrich N, Vogel J (2013)

The EMBO Journal 32 (13): 1802-4

Small RNA-Mediated Activation of Sugar Phosphatase mRNA Regulates Glucose Homeostasis

Papenfort K, Sun Y, Miyakoshi M, Vanderpool CK, Vogel J (2013)

Cell 153 (2): 426-437

Modular polynucleotides for ligand-controlled regulatory systems

Smolke CD, Win MN, Beisel CL (2013)

Patent (US8367815B2)

A small RNA serving both the Hfq and CsrA regulons

Holmqvist E, Vogel J (2013)

Genes & Development 27 (10): 1073-8

Regulatory Mechanisms of Special Significance: Role of Small RNAs in Virulence Regulation

Papenfort K, Corcoran CP, Gupta SK, Miyakoshi M, Heidrich N, Chao Y, Fröhlich KS, Ziebuhr W, Böhm A, Vogel J, Sharma CM (2013)

In: Regulation of Bacterial Virulence (eds Darwin AJ, Vasil ML): 493-527

RNA-mediated regulation in pathogenic bacteria

Caldelari I, Chao Y, Romby P, Vogel J (2013)

Cold Spring Harbor Perspectives In Medicine 3 (9): a010298

Bacterial regulatory mechanisms: the gene and beyond

Bassler B, Vogel J (2013)

Current Opinion in Microbiology 16 (2): 109-11

Comparative genomics boosts target prediction for bacterial small RNAs

Wright PR, Richter AS, Papenfort K, Mann M, Vogel J, Hess WR, Backofen R, Georg J (2013)

PNAS 110 (37): E3487-96

Identification of LIN28B-bound mRNAs reveals features of target recognition and regulation

Graf R, Munschauer M, Mastrobuoni G, Mayr F, Heinemann U, Kempa S, Rajewsky N, Landthaler M (2013)

RNA Biology 10 (7): 1146-59

Understanding and exploiting feedback in synthetic biology

Afroz T, Beisel CL (2013)

Chemical Engineering Science 103: 79-90

Alexander Böhm (1971-2012)

Boos W, Parkinson JS, Jenal U, Vogel J, Søgaard-Andersen L (2013)

Molecular Microbiology 88 (2): 219-21

Improved quantification of HIV-1-infected CD4+ T cells using an optimised method of intracellular HIV-1 gag p24 antigen detection

Yang H, Yorke E, Hancock G, Clutton G, Sande N, Angus B, Smyth RP, Mak J, Dorrell L (2013)

Journal of Immunological Methods 391 (1-2): 174-8

Intracellular Dynamics of HIV Infection

Petravic J, Ellenberg P, Chan M, Paukovics G, Smyth RP, Mak J, Davenport MP (2013)

Journal of Virology 88 (2): 1113-24

Differential activation and functional specialization of miR-146 and miR-155 in innate immune sensing

Schulte LN, Westermann AJ, Vogel J (2013)

Nucleic Acids Research 41 (1): 542-53

A functional sequence-specific interaction between influenza A virus genomic RNA segments

Gavazzi C, Yver M, Isel C, Smyth RP, Rosa-Calatrava M, Lina B, Moulès V, Marquet R (2013)

PNAS 110 (41): 16604-9

Rfam 11.0: 10 years of RNA families

Burge SW, Daub J, Eberhardt R, Tate J, Barquist L, Nawrocki EP, Eddy SR, Gardner PP, Bateman A (2013)

Nucleic Acids Research 41 (Database issue): D226-32

RNA-seq reveals the RNA binding proteins, Hfq and RsmA, play various roles in virulence, antibiotic production and genomic flux in Serratia sp. ATCC 39006

Wilf NM, Reid AJ, Ramsay JP, Williamson NR, Croucher NJ, Gatto L, Hester SS, Goulding D, Barquist L, Lilley KS, …, Dougan G, Salmond GP (2013)

BMC Genomics 14: 822

A comparison of dense transposon insertion libraries in the Salmonella serovars Typhi and Typhimurium

Barquist L, Langridge GC, Turner DJ, Phan M, Turner AK, Bateman A, Parkhill J, Wain J, Gardner PP (2013)

Nucleic Acids Research 41 (8): 4549-64

Dominant role of nucleotide substitution in the diversification of serotype 3 pneumococci over decades and during a single infection

Croucher NJ, Mitchell AM, Gould KA, Inverarity D, Barquist L, Feltwell T, Fookes MC, Harris SR, Dordel J, Salter SJ, …, Mitchell TJ, Bentley SD (2013)

PLOS Genetics 9 (10): e1003868

The agr locus regulates virulence and colonization genes in Clostridium difficile 027

Martin MJ, Clare S, Goulding D, Faulds-Pain A, Barquist L, Browne HP, Pettit LJ, Dougan G, Lawley TD, Wren BW (2013)

Journal of Bacteriology 195 (16): 3672-81

Approaches to querying bacterial genomes with transposon-insertion sequencing

Barquist L, Boinett CJ, Cain AK (2013)

RNA Biology 10 (7): 1161-9

Genome and transcriptome adaptation accompanying emergence of the definitive type 2 host-restricted Salmonella enterica serovar Typhimurium pathovar

Kingsley RA, Kay S, Connor T, Barquist L, Sait L, Holt KE, Sivaraman K, Wileman TM, Goulding D, Clare S, …, Parkhill J, Dougan G (2013)

mBio 4 (5): e00565-13

Characterization of the yehUT two-component regulatory system of Salmonella enterica Serovar Typhi and Typhimurium

Wong VK, Pickard DJ, Barquist L, Sivaraman K, Page AJ, Hart PJ, Arends MJ, Holt KE, Kane L, Mottram LF, …, Kingsley RA, Dougan G (2013)

PLOS One 8 (12): e84567

2012

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

Baltz AG, Munschauer M, Schwanhäusser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, …, Dieterich C, Landthaler M (2012)

Molecular Cell 46 (5): 674-90

FMRP targets distinct mRNA sequence elements to regulate protein expression

Ascano M, Mukherjee N, Bandaru P, Miller JB, Nusbaum JD, Corcoran DL, Langlois C, Munschauer M, Dewell S, Hafner M, …, Ohler U, Tuschl T (2012)

Nature 492 (7429): 382-6

The seed region of a small RNA drives the controlled destruction of the target mRNA by the endoribonuclease RNase E

Bandyra KJ, Said N, Pfeiffer V, Górna MW, Vogel J, Luisi BF (2012)

Molecular Cell 47 (6): 943-53

Dual RNA-seq of pathogen and host

Westermann AJ, Gorski SA, Vogel J (2012)

Nature Reviews Microbiology 10 (9): 618-30

Surface-associated motility, a common trait of clinical isolates of Acinetobacter baumannii, depends on 1,3-diaminopropane

Skiebe E, de Berardinis V, Morczinek P, Kerrinnes T, Faber F, Lepka D, Hammer B, Zimmermann O, Ziesing S, Wichelhaus TA, …, Pfeifer Y, Wilharm G (2012)

International Journal of Medical Microbiology 302 (3): 117-28

Transgene regulation in plants by alternative splicing of a suicide exon

Hickey SF, Sridhar M, Westermann AJ, Qin Q, Vijayendra P, Liou G, Hammond MC (2012)

Nucleic Acids Research 40 (10): 4701-10

Multiple factors dictate target selection by Hfq-binding small RNAs

Beisel CL, Updegrove TB, Janson BJ, Storz G (2012)

The EMBO Journal 31 (8): 1961-74

The mammalian microRNA response to bacterial infections

Eulalio A, Schulte LN, Vogel J (2012)

RNA Biology 9 (6): 742-50

Experimental tools to identify RNA-protein interactions in Helicobacter pylori

Rieder R, Reinhardt R, Sharma CM, Vogel J (2012)

RNA Biology 9 (4): 520-31

Small RNAs of the Bradyrhizobium/Rhodopseudomonas lineage and their analysis

Madhugiri R, Pessi G, Voss B, Hahn J, Sharma CM, Reinhardt R, Vogel J, Hess WR, Fischer H, Evguenieva-Hackenberg E (2012)

RNA Biology 9 (1): 47-58

The ancestral SgrS RNA discriminates horizontally acquired Salmonella mRNAs through a single G-U wobble pair

Papenfort K, Podkaminski D, Hinton JC, Vogel J (2012)

PNAS 109 (13): E757-64

The transcriptional landscape and small RNAs of Salmonella enterica serovar Typhimurium

Kröger C, Dillon SC, Cameron AD, Papenfort K, Sivasankaran SK, Hokamp K, Chao Y, Sittka A, Hébrard M, Händler K, …, Vogel J, Hinton JC (2012)

PNAS 109 (20): E1277-86

RelA protein stimulates the activity of RyhB small RNA by acting on RNA-binding protein Hfq

Argaman L, Elgrably-Weiss M, Hershko T, Vogel J, Altuvia S (2012)

PNAS 109 (12): 4621-6

Global regulatory functions of the Staphylococcus aureus endoribonuclease III in gene expression

Lioliou E, Sharma CM, Caldelari I, Helfer A, Fechter P, Vandenesch F, Vogel J, Romby P (2012)

PLOS Biology 8 (6): e1002782

The Primary Transcriptome of Barley Chloroplasts: Numerous Noncoding RNAs and the Dominating Role of the Plastid-Encoded RNA Polymerase

Zhelyazkova P, Sharma CM, Förstner KU, Liere K, Vogel J, Börner T (2012)

The Plant Cell 24 (1): 123-36

Superfolder GFP reporters validate diverse new mRNA targets of the classic porin regulator, MicF RNA

Corcoran CP, Podkaminski D, Papenfort K, Urban JH, Hinton JC, Vogel J (2012)

Molecular Microbiology 84 (3): 428-45

The csgD mRNA as a hub for signal integration via multiple small RNAs

Boehm A, Vogel J (2012)

Molecular Microbiology 84 (1): 1-5

An atlas of Hfq-bound transcripts reveals 3' UTRs as a genomic reservoir of regulatory small RNAs

Chao Y, Papenfort K, Reinhardt R, Sharma CM, Vogel J (2012)

The EMBO Journal 31 (20): 4005-19

Use of aptamer tagging to identify in vivo protein binding partners of small regulatory RNAs

Corcoran CP, Rieder R, Podkaminski D, Hofmann B, Vogel J (2012)

In: Bacterial Regulatory RNA: Methods and protocols (ed Keiler KC) 905: 177-200

Hfq-associated Regulatory Small RNAs

Corcoran CP, Papenfort K, Vogel J (2012)

In: Regulatory RNAs in Prokaryotes (eds Marchfelder A, Hess WR): 15-50

Differential RNA Sequencing (dRNA-Seq): Deep-Sequencing-Based Analysis of Primary Transcriptomes

Borries A, Vogel J, Sharma CM (2012)

In: Tag-based next generation sequencing (eds Kahl G, Harbers M ) 316: 109-121

The Origin of Genetic Diversity in HIV-1

Smyth RP, Davenport MP, Mak J (2012)

Virus Research 169 (2): 415-29

A high-resolution view of genome-wide pneumococcal transformation

Croucher NJ, Harris SR, Barquist L, Parkhill J, Bentley SD (2012)

PLOS Pathogens 8 (6): e1002745

HandAlign: Bayesian multiple sequence alignment, phylogeny and ancestral reconstruction

Westesson O, Barquist L, Holmes I (2012)

Bioinformatics 28 (8): 1170-1

2011

The base pairing RNA Spot 42 participates in a multi-output feedforward loop to help enact catabolite repression in Escherichia coli

Beisel CL, Storz G (2011)

Molecular Cell 41 (3): 286-97

Hfq and its constellation of RNA

Vogel J, Luisi BF (2011)

Nature Reviews Microbiology 9 (8): 578-89

Regulation by small RNAs in bacteria: expanding frontiers

Storz G, Vogel J, Wassarman KM (2011)

Molecular Cell 43 (6): 880-91

Sweet Business: Spot42 RNA networks with CRP to Modulate Catabolite Repression

Papenfort K, Vogel J (2011)

Molecular Cell 41 (3): 245-6

CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III

Deltcheva E, Chylinski K, Sharma CM, Gonzales K, Chao Y, Pirzada ZA, Eckert MR, Vogel J, Charpentier E (2011)

Nature 471 (7340): 602-7

Design of small molecule-responsive microRNAs based on structural requirements for Drosha processing

Beisel CL, Chen YY, Culler SJ, Hoff KG, Smolke CD (2011)

Nucleic Acids Research 39 (7): 2981-94

Discriminating tastes: physiological contributions of the Hfq-binding small RNA Spot 42 to catabolite repression

Beisel CL, Storz G (2011)

RNA Biology 8 (5): 766-70

A conserved RpoS-dependent small RNA controls the synthesis of major porin OmpD

Fröhlich KS, Papenfort K, Berger AA, Vogel J (2011)

Nucleic Acids Research 40 (8): 3623-40

Helicobacter pylori interferes with an embryonic stem cell micro RNA cluster to block cell cycle progression

Belair C, Baud J, Chabas S, Sharma CM, Vogel J, Staedel C, Darfeuille F (2011)

Silence 2 (1): 7

Small RNAs endow a transcriptional activator with essential repressor functions for single-tier control of a global stress regulon

Gogol EB, Rhodius VA, Papenfort K, Vogel J, Gross CA (2011)

PNAS 108 (31): 12875-80

An experimentally anchored map of transcriptional start sites in the model cyanobacterium Synechocystis sp. PCC6803

Mitschke J, Georg J, Scholz I, Sharma CM, Dienst D, Bantscheff J, Voss B, Steglich C, Wilde A, Vogel J, Hess WR (2011)

PNAS 108 (5): 2124-9

A candidate approach implicates the secreted Salmonella effector protein SpvB in P-body disassembly

Eulalio A, Fröhlich KS, Mano M, Giacca M, Vogel J (2011)

PLOS One 6 (3): e17296

Genome-wide transcriptome analysis of the plant pathogen Xanthomonas identifies sRNAs with putative virulence functions

Schmidtke C, Findeiß S, Sharma CM, Kuhfuß J, Hoffmann S, Vogel J, Stadler PF, Bonas U (2011)

Nucleic Acids Research 40 (5): 2020-31

Pervasive post-transcriptional control of genes involved in amino acid metabolism by the Hfq-dependent GcvB small RNA

Sharma CM, Papenfort K, Pernitzsch SR, Mollenkopf H, Hinton JC, Vogel J (2011)

Molecular Microbiology 81 (5): 1144-65

Contribution of Hfq to photooxidative stress resistance and global regulation in Rhodobacter sphaeroides

Berghoff BA, Glaeser J, Sharma CM, Zobawa M, Lottspeich F, Vogel J, Klug G (2011)

Molecular Microbiology 80 (6): 1479-95

Microbes at their best: first Mol Micro Meeting Würzburg

Böhm A, Papenfort K, Lopez D, Vogel J (2011)

Molecular Microbiology 82 (4): 797-806

The transcriptional landscape of Chlamydia pneumoniae

Albrecht M, Sharma CM, Dittrich MT, Müller T, Reinhardt R, Vogel J, Rudel T (2011)

Genome Biology 12 (10): R98

Analysis of the host microRNA response to Salmonella uncovers the control of major cytokines by the let-7 family

Schulte LN, Eulalio A, Mollenkopf H, Reinhardt R, Vogel J (2011)

The EMBO Journal 30 (10): 1977-89

8-Modified-2'-deoxyadenosine analogues induce delayed polymerization arrest during HIV-1 reverse transcription

Vivet-Boudou V, Isel C, Sleiman M, Smyth RP, Ben Gaied N, Barhoum P, Laumond G, Bec G, Götte M, Mak J, …, Burger A, Marquet R (2011)

PLOS One 6 (11): e27456

Early events of HIV-1 infection: can signaling be the next therapeutic target?

Jones KL, Smyth RP, Pereira CF, Cameron PU, Lewin SR, Jaworowski A, Mak J (2011)

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 6 (2): 269-83

Labeling of multiple HIV-1 proteins with the biarsenical-tetracysteine system

Pereira CF, Ellenberg PC, Jones KL, Fernandez TL, Smyth RP, Hawkes DJ, Hijnen M, Vivet-Boudou V, Marquet R, Johnson I, Mak J (2011)

PLOS One 6 (2): e17016

RNIE: genome-wide prediction of bacterial intrinsic terminators

Gardner PP, Barquist L, Bateman A, Nawrocki EP, Weinberg Z (2011)

Nucleic Acids Research 39 (14): 5845-52

2010

Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP

Hafner M, Landthaler M, Burger L, Khorshid M, Hausser J, Berninger P, Rothballer A, Ascano M, Jungkamp A, Munschauer M, …, Zavolan M, Tuschl T (2010)

Cell 141 (1): 129-41

Base pairing small RNAs and their roles in global regulatory networks

Beisel CL, Storz G (2010)

FEMS Microbiology Reviews 34 (5): 866-82

Regulatory RNA in bacterial pathogens

Papenfort K, Vogel J (2010)

Cell Host & Microbe 8 (1): 116-27

The primary transcriptome of the major human pathogen Helicobacter pylori

Sharma CM, Hoffmann S, Darfeuille F, Reignier J, Findeiss S, Sittka A, Chabas S, Reiche K, Hackermüller J, Reinhardt R, Stadler PF, Vogel J (2010)

Nature 464 (7286): 250-5

A simple and rapid method of bacterial transformation

Wilharm G, Lepka D, Faber F, Hofmann J, Kerrinnes T, Skiebe E (2010)

Journal of Microbiological Methods 80 (2): 215-6

Orbus hercynius gen. nov., sp. nov., isolated from faeces of wild boar, is most closely related to members of the orders 'Enterobacteriales' and Pasteurellales

Volkmann M, Skiebe E, Kerrinnes T, Faber F, Lepka D, Pfeifer Y, Holland G, Bannert N, Wilharm G (2010)

International Journal of Systematic and Evolutionary Microbiology 60 (Pt 11): 2601-2605

Polypyrimidine tract-binding protein homologues from Arabidopsis underlie regulatory circuits based on alternative splicing and downstream control

Stauffer E, Westermann A, Wagner G, Wachter A (2010)

The Plant journal : for cell and molecular biology 64 (2): 243-55

The small RNAs of Salmonella

Javayel S, Papenfort K, Vogel J (2010)

In: Salmonella: From Genome to Function (ed Prowollik S)

PAR-CliP--a method to identify transcriptome-wide the binding sites of RNA binding proteins

Hafner M, Landthaler M, Burger L, Khorshid M, Hausser J, Berninger P, Rothballer A, Ascano M, Jungkamp A, Munschauer M, …, Zavolan M, Tuschl T (2010)

Journal of Visualized Experiments (41): pii: 2034

Analysis of A to I editing of miRNA in macrophages exposed to salmonella

Heale BS, Eulalio A, Schulte LN, Vogel J, O'Connell MA (2010)

RNA Biology 7 (5): 621-7

Evidence for an autonomous 5′ target recognition domain in an Hfq-associated small RNA

Papenfort K, Bouvier M, Mika F, Sharma CM, Vogel J (2010)

PNAS 107 (47): 20435-40

Identification of regulatory RNAs in Bacillus subtilis

Irnov I, Sharma CM, Vogel J, Winkler WC (2010)

Nucleic Acids Research 38 (19): 6637-51

Deep sequencing-based discovery of the Chlamydia trachomatis transcriptome

Albrecht M, Sharma CM, Reinhardt R, Vogel J, Rudel T (2010)

Nucleic Acids Research 38 (3): 868-77

Experimental discovery of small RNAs in Staphylococcus aureus reveals a riboregulator of central metabolism

Bohn C, Rigoulay C, Chabelskaya S, Sharma CM, Marchais A, Skorski P, Borezée-Durant E, Barbet R, Jacquet E, Jacq A, …, Vogel J, Bouloc P (2010)

Nucleic Acids Research 38 (19): 6620-36

Small RNAs promote mRNA stability to activate the synthesis of virulence factors

Podkaminski D, Vogel J (2010)

Molecular Microbiology 78 (6): 1327-31

The role of Hfq in bacterial pathogens

Chao Y, Vogel J (2010)

Current Opinion in Microbiology 13 (1): 24-33

Accurately measuring recombination between closely related HIV-1 genomes

Schlub TE, Smyth RP, Grimm AJ, Mak J, Davenport MP (2010)

PLOS Computational Biology 6 (4): e1000766

Reducing chimera formation during PCR amplification to ensure accurate genotyping

Smyth RP, Schlub TE, Grimm A, Venturi V, Chopra A, Mallal S, Davenport MP, Mak J (2010)

Gene 469 (1-2): 45-51

Microfluidic sorting and multimodal typing of cancer cells in self-assembled magnetic arrays

Saliba AE, Saias L, Psychari E, Minc N, Simon D, Bidard F, Mathiot C, Pierga J, Fraisier V, Salamero J, …, Malaquin L, Viovy J (2010)

PNAS 107 (33): 14524-9

2009

Coding sequence targeting by MicC RNA reveals bacterial mRNA silencing downstream of translational initiation

Pfeiffer V, Papenfort K, Lucchini S, Hinton JC, Vogel J (2009)

Nature Structural & Molecular Biology 16 (8): 840-6

CsrA and CsrB are required for the post-transcriptional control of the virulence-associated effector protein AvrA of Salmonella enterica

Kerrinnes T, Zelas ZB, Streckel W, Faber F, Tietze E, Tschäpe H, Yaron S (2009)

International Journal of Medical Microbiology 299 (5): 333-41

A small RNA cascade regulates aminosugar synthesis

Vogel J (2009)

In: Nova Acta Leopoldina 378: 41-50

Cellules tumorales circulantes et cancer du sein : méthodes de détection et résultats cliniques

Bidard F, Saliba AE, Saias L, Degeorges A, Cremoux Pd, Viovy J, Vincent-Salomon A, Mathiot C, Pierga J, Gramont A (2009)

Bulletin du Cancer 96 (1): 73-86

Synthetic control of a fitness tradeoff in yeast nitrogen metabolism

Bayer TS, Hoff KG, Beisel CL, Lee JJ, Smolke CD (2009)

Journal of Biological Engineering 3: 1

Design Principles for Riboswitch Function

Beisel CL, Smolke CD (2009)

PLOS Computational Biology 5 (4): e1000363

A green fluorescent protein (GFP)-based plasmid system to study post-transcriptional control of gene expression in vivo

Urban JH, Vogel J (2009)

In: Riboswitches: Methods and protocols (ed Serganov A), Methods Mol Biol 540: 301-19

Deep sequencing of Salmonella RNA associated with heterologous Hfq proteins in vivo reveals small RNAs as a major target class and identifies RNA processing phenotypes

Sittka A, Sharma CM, Rolle K, Vogel J (2009)

RNA Biology 6 (3): 266-75

Multiple target regulation by small noncoding RNAs rewires gene expression at the post-transcriptional level

Papenfort K, Vogel J (2009)

Research in Microbiology 160 (4): 278-87

Deep sequencing analysis of the Methanosarcina mazei Gö1 transcriptome in response to nitrogen availability

Jäger D, Sharma CM, Thomsen J, Ehlers C, Vogel J, Schmitz RA (2009)

PNAS 106 (51): 21878-82

In vivo expression and purification of aptamer-tagged small RNA regulators

Said N, Rieder R, Hurwitz R, Deckert J, Urlaub H, Vogel J (2009)

Nucleic Acids Research 37 (20): e133-e133

An RNA trap helps bacteria get the most out of chitosugars

Vogel J (2009)

Molecular Microbiology 73 (5): 737-41

A rough guide to the non-coding RNA world of Salmonella

Vogel J (2009)

Molecular Microbiology 71 (1): 1-11

Regulatory RNAs in prokaryotes: here, there and everywhere

Narberhaus F, Vogel J (2009)

Molecular Microbiology 74 (2): 261-9

Photooxidative stress-induced and abundant small RNAs in Rhodobacter sphaeroides

Berghoff BA, Glaeser J, Sharma CM, Vogel J, Klug G (2009)

Molecular Microbiology 74 (6): 1497-512

Specific and pleiotropic patterns of mRNA regulation by ArcZ, a conserved, Hfq-dependent small RNA

Papenfort K, Said N, Welsink T, Lucchini S, Hinton JC, Vogel J (2009)

Molecular Microbiology 74 (1): 139-158

Acid stress activation of the sigma(E) stress response in Salmonella enterica serovar Typhimurium

Muller C, Bang I, Velayudhan J, Karlinsey J, Papenfort K, Vogel J, Fang FC (2009)

Molecular Microbiology 71 (5): 1228-38

Fast mapping of short sequences with mismatches, insertions and deletions using index structures

Hoffmann S, Otto C, Kurtz S, Sharma CM, Khaitovich P, Vogel J, Stadler PF, Hackermüller J (2009)

PLOS Computational Biology 5 (9): e1000502

Experimental approaches for the discovery and characterization of regulatory small RNA

Sharma CM, Vogel J (2009)

Current Opinion in Microbiology 12 (5): 536-46

Activation of gene expression by small RNA

Fröhlich KS, Vogel J (2009)

Current Opinion in Microbiology 12 (6): 674-82

The A-rich RNA sequences of HIV-1 pol are important for the synthesis of viral cDNA

Keating CP, Hill MK, Hawkes DJ, Smyth RP, Isel C, Le S, Palmenberg AC, Marshall JA, Marquet R, Nabel GJ, Mak J (2009)

Nucleic Acids Research 37 (3): 945-56

Evolutionary modeling and prediction of non-coding RNAs in Drosophila

Bradley RK, Uzilov AV, Skinner ME, Bendana YR, Barquist L, Holmes I (2009)

PLOS One 4 (8): e6478

2008

Model-guided design of ligand-regulated RNAi for programmable control of gene expression

Beisel CL, Bayer TS, Hoff KG, Smolke CD (2008)

Molecular Systems Biology 4: 224

Two seemingly homologous noncoding RNAs act hierarchically to activate glmS mRNA translation

Urban JH, Vogel J (2008)

PLOS Biology 6 (3): e64

Small RNA binding to 5' mRNA coding region inhibits translational initiation

Bouvier M, Sharma CM, Mika F, Nierhaus KH, Vogel J (2008)

Molecular Cell 32 (6): 827-837

Noncoding RNA control of the making and breaking of sugars

Görke B, Vogel J (2008)

Genes & Development 22 (21): 2914-25

The cyanobacterial homologue of the RNA chaperone Hfq is essential for motility of Synechocystis sp. PCC 6803

Dienst D, Dühring U, Mollenkopf H, Vogel J, Golecki J, Hess WR, Wilde A (2008)

Microbiology 154 (Pt 10): 3134-3143

RNA: Noncoding

Henry AA, Vogel J (2008)

In: Wiley Encyclopedia of Chemical Biology (ed Begley TP) 22: 2183

Deep sequencing analysis of small noncoding RNA and mRNA targets of the global post-transcriptional regulator, Hfq

Sittka A, Lucchini S, Papenfort K, Sharma CM, Rolle K, Binnewies TT, Hinton JC, Vogel J (2008)

PLOS Genetics 4 (8): e1000163

A new Vibrio cholerae sRNA modulates colonization and affects release of outer membrane vesicles

Song T, Mika F, Lindmark B, Liu Z, Schild S, Bishop A, Zhu J, Camilli A, Johansson J, Vogel J, Wai SN (2008)

Molecular Microbiology 70 (1): 100-111

Systematic deletion of Salmonella small RNA genes identifies CyaR, a conserved CRP-dependent riboregulator of OmpX synthesis

Papenfort K, Pfeiffer V, Lucchini S, Sonawane A, Hinton JC, Vogel J (2008)

Molecular Microbiology 68 (4): 890-906

A Glimpse at the Evolution of Virulence Control

Sittka A, Vogel J (2008)

Cell Host & Microbe 4 (4): 310-312

xREI: a phylo-grammar visualization webserver

Barquist L, Holmes I (2008)

Nucleic Acids Research 36 (Web Server issue): W65-W69

2007

An antisense RNA inhibits translation by competing with standby ribosomes

Darfeuille F, Unoson C, Vogel J, Wagner EG (2007)

Molecular Cell 26 (3): 381-92

A small RNA regulates multiple ABC transporter mRNAs by targeting C/A-rich elements inside and upstream of ribosome-binding sites

Sharma CM, Darfeuille F, Plantinga TH, Vogel J (2007)

Genes & Development 21 (21): 2804-17

Influence of poly(L-lysine) on the structure of dipalmitoylphosphatidylglycerol/water dispersions studied by X-ray scattering

Förster G, Schwieger C, Faber F, Weber T, Blume A (2007)

European Biophysics Journal 36 (4-5): 425-35

A small non-coding RNA of the invasion gene island (SPI-1) represses outer membrane protein synthesis from the Salmonella core genome

Pfeiffer V, Sittka A, Tomer R, Tedin K, Brinkmann V, Vogel J (2007)

Molecular Microbiology 66 (5): 1174-91

Target identification of small noncoding RNAs in bacteria

Vogel J, Wagner EG (2007)

Current Opinion in Microbiology 10 (3): 262-70

2006

Lack of angiotensin II conversion to angiotensin III increases water but not alcohol consumption in aminopeptidase A-deficient mice

Faber F, Gembardt F, Sun X, Mizutani S, Siems WE, Walther T (2006)

Regulatory Peptides 136 (1-3): 130-7

2005

Hfq-dependent regulation of OmpA synthesis is mediated by an antisense RNA

Udekwu KI, Darfeuille F, Vogel J, Reimegård J, Holmqvist E, Wagner EG (2005)

Genes & Development 19 (19): 2355-66

Approaches to Identify Novel Non-messenger RNAs in Bacteria and to Investigate their Biological Functions: Functional Analysis of Identified Non-mRNAs

Gerhart E, Wagner H, Vogel J (2005)

In: Handbook of RNA Biochemistry (eds Hartmann RK, Bindereif A, Schön A, Westhof E) 2: 614-642

2004

The small RNA IstR inhibits synthesis of an SOS-induced toxic peptide

Vogel J, Argaman L, Wagner EG, Altuvia S (2004)

Current Biology 14 (24): 2271-6

Nanotechnology serving biochips – The Toulouse example

Vieu C, Malaquin L, Thibault C, Saliba AE, Daran E, Dildan M, Carcenac F, Leberre V, Trevisiol E, François JM (2004)

Biofutur (250): 41-45

2003

Noncoding RNAs encoded by bacterial chromosomes

Wagner EG, Vogel J (2003)

In: Noncoding RNAs (eds Barciszewski J, Erdmann V): 243-259

Experimental and computational analysis of transcriptional start sites in the cyanobacterium Prochlorococcus MED4

Vogel J, Axmann IM, Herzel H, Hess WR (2003)

Nucleic Acids Research 31 (11): 2890-9

RNomics in Escherichia coli detects new sRNA species and indicates parallel transcriptional output in bacteria

Vogel J, Bartels V, Tang TH, Churakov G, Slagter-Jäger JG, Hüttenhofer A, Wagner EG (2003)

Nucleic Acids Research 31 (22): 6435-43

2002

Lariat formation and a hydrolytic pathway in plant chloroplast group II intron splicing

Vogel J, Börner T (2002)

The EMBO Journal 21 (14): 3794-803

Cochlear whole mount in situ hybridization: identification of longitudinal and radial gradients

Judice TN, Nelson NC, Beisel CL, Delimont DC, Fritzsch B, Beisel KW (2002)

Brain Research Protocols 9 (1): 65-76

2001

Complete 5' and 3' end maturation of group II intron-containing tRNA precursors

Vogel J, Hess WR (2001)

RNA 7 (2): 285-92

Novel small RNA-encoding genes in the intergenic regions of Escherichia coli

Argaman L, Hershberg R, Vogel J, Bejerano G, Wagner EG, Margalit H, Altuvia S (2001)

Current Biology 11 (12): 941-50

The ins and outs of group II introns

Bonen L, Vogel J (2001)

Trends In Genetics 17 (6): 322-31